THEME: "Frontiers in Neuroscience and Brain Disorders Research"
Interventional Health, USA
Title: Treatment of Chronic Muscle Spasm and Pain with the CMECD® Procedure
Coletti received a BA from Georgetown University
College of Arts and Sciences. He received a Master of Arts from Hofstra
University. He received his MD from State University of New York at
Downstate. His medical internship and
residency was performed at Nassau County Medical Center in East Meadow, NY. He
did two years of cardiology fellowship at Columbia Presbyterian Medical Center
in New York and then transferred to Westchester County Medical Center where he
completed one year of Interventional Cardiology fellowship. He was awarded
FACC, FASNC, and FSCAI fellowship status. Current interest is chronic muscle
spasm and pain. He has proposed The Ischemic Model of Chronic Muscle Spasm and
developed the CMECD® procedure for treatment of chronic pain.
It has been noted by multiple
researchers that there is Spontaneous Electrical Activity (SEA) at painful
trigger points. This author has studied chronic muscle spasm and found that SEA
is always present and appears to be the cause for the chronic nature of muscle
spasm and resulting chronic pain. Chronic muscle spasm and resulting chronic
pain can last for years and cases where the spasm lasted for decades were not
only found but successfully treated with the CMECD® procedure. This procedure
consists of EMG guidance searching for the SEA and using a combination of
phenoxybenzamine, Lidocaine and dexamethasone to extinguish the SEA. Large
areas of muscle often need to be treated. Thanks to lidocaine acting as an
antiarrhythmic, the SEA is extinguished within seconds and the phenoxybenzamine
then takes over after about one hour. With the resolution of the SEA, the
muscle can immediately relax. The phenoxybenzamine forms a covalent bond on the
alpha motoneuron receptor and the result is a duration of action of 2-3 months.
This is enough time for the muscle to recover the prolonged effect of ischemia
resulting from the prolonged spasm. Muscles treated in this fashion need only a
single injection. Recurrences are rare and only occur if there is a repeat
overuse or traumatic injury. The CMECD® procedure is available for use by any
medical caregiver that is licensed to give injections. The ability to
permanently relieve chronic pain without the use of opioid drugs should prompt
interest in this procedure.